LM of transitional epithelium in a distended bladder. Two or three layers of nucleated epithelial cells are typical of the bladder filled with urine. The largest, most superficial cells (SC) are round and bulge into the lumen (*). Cells more intermediate in position are cuboidal. Basal cells, the smallest and most closely packed, abut a thin basement membrane (arrows). The lamina propria is made of loose connective tissue. 375×. H&E.