Pulmonary Vascular Resistance
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Pulmonary Vascular Resistance
Figure 13.2 • Pulmonary Vascular Resistance – Resistance in the pulmonary circulation is affected by pulmonary artery pressure and blood flow, lung volume, and chemical and humoral substances. Elevation of pulmonary artery pressure causes distension of vessels and recruitment of capillaries that are otherwise collapsed (A), resulting in reduced resistance. An increase in lung volume causes traction and thus distension of extra–alveolar vessels, but results in compression of alveolar capillaries (B); the combination of these two effects results in lowest pulmonary vascular resistance at intermediate lung volumes. Pulmonary vessels also constrict and dilate in response to a number of chemical and humoral mediators (C).

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  This Illustration was Published In
Netter's Essential Physiology
Netter's Essential Physiology
Author: Susan E. Mulroney, Adam K. Myers
Chapter: Pulmonary Ventilation and Perfusion and Diffusion of Gases
Page: 148
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